WebFeb 3, 2024 · The molecular interactions between the surfaces of cocrystals [i.e., flufenamic acid and theophylline (FFA-TP), flufenamic acid and nicotinamide (FFA … WebSep 6, 2024 · A contribution of crystal structure, mechanical moduli, and macroscopic compression properties of flufenamic acid (FFA) and its cocrystal with nicotinamide (NIC) was evaluated to predict...
Solubility Test Results Download Table - ResearchGate
WebMay 1, 2024 · Two novel pharmaceutical co-crystals of anti-inflammatory drug flufenamic acid (FFA) with 2-chloro-4-nitrobenzoic acid (CNB) and ethenzamide (ETZ) have been … Web1.1.1 The p K a-based tool. The use of the p K a rule to predict cocrystal formation is based on the fact that a cocrystal can be distinguished from a salt by whether a proton transfer has occurred from an acid to a base. The p K a describes the tendency of an acid, or a conjugate acid of a base, to give up a proton. It has been suggested that a Δp K a [p K a … book of mirrors
Flufenamic acid C14H10F3NO2 - PubChem
WebSep 2008 - May 20145 years 9 months. Group Leader Polymorph, Salt, and Cocrystal Screening. Scientific Method Development in Polymorph Prediction, Structure Solution from PXRD, Rietveld Methods ... WebCocrystallization with flufenamic acid: comparison of ... Cocrystal Coformer MP (°C)a Cocrystal MP (°C) FFA TP 274-275 202-204 FFA NA 130-132 138-140 FFA 2-pyridone 105-107 110-114 FFA BP 111-114 120-123 aMP data was taken from Sigma-Aldrich chemicals catalogue. WebInsight into Flufenamic Acid Cocrystal Dissolution in the Presence of a Polymer in Solution: from Single Crystal to Powder Dissolution Minshan Guo,† Ke Wang,† Ning Qiao,‡ László Fábián,§ Ghazala Sadiq,⊥ and Mingzhong Li *,† † School of Pharmacy, De Montfort University, Leicester, LE1 9BH, U.K. ‡ College of Materials Science and Engineering, … god\u0027s preceptive will