WebSep 3, 2024 · In this study, the buoyancy properties of promethazine tablets containing okra gum and gas-generating agents sodium carbonate and bicarbonate were evaluated to determine if a new floating drug delivery system for promethazine hydrochloride is feasible. WebJan 6, 2024 · The following formula was used for calculating swelling index (SI): Swelling Index = (weight of tablet at time-weight of tablet before immersion)/ (weight of tablet before immersion) × 100. 2.8 In vitro dissolution studies
FORMULATION AND EVALUATION OF FLOATING TABLETS OF OFLOXA…
WebTwelve floating tablets formulations, each containing 200 mg of MbH, were prepared by a direct compression method. Briefly, 200 mg of the drug, polymer, and other additives as mentioned in Table 1 were mixed in incremental amounts, and then the mixture was screened through a 40-mesh sieve (425 μm). WebFormulation Tmax (h) Cmax AUC Various trial batches were prepared using a different concentration of (ng/ml) (ng h‑1 ml‑1) selected polymers to obtain an optimized tablet of around 3–4 kg/cm2 Marketed SR 4.0±0.67 … how many inhalations are in advair diskus
FORMULATION AND EVALUATION OF FLOATING TABLETS …
WebTablet floatation was achieved by an effervescent mechanism. Citric acid at different concentrations was used in formulations to provide an acidic microenvironment. The prepared tablets were characterized for hardness, weight variation, thickness, friability, floating lag time, and dissolution. WebThe cinnarizine floating tablet as floating tablet remains for percentage friability (f) was calculated by the formula: longer period of time in stomach which provides larger acidic environment and thereby it increases the … WebDec 1, 2024 · The present research work was aimed to formulate floating tablets of mincycline hydrochloride. Minocycline hydrochloride belongs to tetracycline group of antibiotics. It has half life of 11–18 h and dose is 50–100 mg twice daily and is soluble in water. It is best absorbed in upper gastrointestinal tract. howard griffith illinois