WebApr 12, 2024 · The ORION-2 trial was a pilot, phase 3, open-label, single-arm, multicenter study conducted in four patients with homozygous familial hypercholesterolemia (HoFH) on maximally tolerated, high-intensity statins and ezetimibe . Inclisiran sodium 300 mg was subcutaneously administered on day 1 in all four patients; three patients also received a ... WebApr 12, 2024 · Combination therapy with moderate-dose statin plus ezetimibe was associated with similar ASCVD rates compared to monotherapy with high-intensity statin therapy among both older adults (≥75 years) and younger adults (<75 years). ... (high-intensity statin monotherapy group). For patients aged ≥75 years, the primary outcome …
ACC/AHA Release Updated Guideline on the Treatment of …
WebMay 8, 2012 · The answers are presently unknown. The SPARCL study reliably showed that high-dose atorvastatin at 80 mg/day reduces the risk of recurrent stroke and other … WebAge 40 to 75, 10-year ASCVD risk ≥ 7.5% (if unable to tolerate high-intensity statin) Age 40 to 75, 10-year ASCVD risk 5 to < 7.5%. Atorvastatin 10-20 mg. Fluvastatin XL 80 mg. … ctu sign in student
Spotlight on statins in diabetes ACP Diabetes Monthly
WebDec 15, 2024 · Doses of Statins (mg) Required to Achieve Various Reductions in LDL-C From Baseline. * 2013 ACC/AHA guidelines: high-intensity statin lowers cholesterol … WebThese statins include atorvastatin at a dose of 10-20 mg/day, rosuvastatin at a dose of 5-10 mg/day, and simvastatin (Zocor) at a dose of 20-40 mg/day. Moderate-intensity statins are typically prescribed for patients with moderately elevated cholesterol levels. To summarize, high-intensity statin therapy, which lowers LDL by more than 50%, is ... WebJun 18, 2024 · The TNT trial (Treatment to New Targets) compared the effects of atorvastatin given at a dose of either 80 mg/d or 10 mg/d. The concentration of LDL … ctu similarity score