Cisplatin pubmed
WebJul 1, 2024 · Using the platinum-based chemotherapy cisplatin as a model for CICI, we show here that cisplatin suppresses nicotinamide adenine dinucleotide (NAD +) levels in the adult female mouse brain in vivo and in human cortical neurons derived from induced pluripotent stem cells in vitro. WebJun 1, 2024 · After completion of gemcitabine and cisplatin, 1500 mg of durvalumab or …
Cisplatin pubmed
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WebCisplatin has dramatically improved the survival rate of cancer patients, but it has also … WebWe demonstrate that cisplatin-induced transition from epithelial to mesenchymal …
WebApr 14, 2024 · Among the extracellular vesicles, apoptotic bodies (ABs) are only formed during the apoptosis and perform a relevant role in the pathogenesis of different diseases. Recently, it has been demonstrated that ABs from human renal proximal tubular HK-2 cells, either induced by cisplatin or by UV light, can lead to further apoptotic death in … WebFor some tumors, cisplatin appears to be superior to carboplatin in terms of therapeutic effectiveness (germ cell tumors, bladder cancer, head and neck cancer), while for others, effectiveness is comparable (lung cancer, ovarian cancer). Toxicity profiles are distinctly different for the two analogu …
WebThe cardiotoxic effect of chemotherapeutic agents as cisplatin has become a major issue recently. Interference with mitochondrial dynamics, biogenesis, redox status, and apoptosis are the most possible underlying mechanisms. Semaglutide is a human glucagon-like peptide-1 receptor agonist (GLP-1R), w … WebKidney injury molecule-1 (KIM-1) is a novel biomarker promising the diagnosis of AKI in early stages. We studied whether urinary and serum KIM-1 (KIM-1 U and KIM-1 S ) concentrations were useful in predicting cisplatin-induced AKI in early stages. Methods: We prospectively analysed 22 patients on cisplatin treatment.
WebJan 28, 2024 · In this study, we sought to provide a comprehensive review of the current state of the science highlighting the use of cisplatin in cancer therapy, with a special emphasis on its molecular mechanisms of action, and treatment modalities including the combination therapy with natural products.
WebGemcitabine and cisplatin chemotherapy is an active combination in the treatment of platinum-resistant ovarian and peritoneal carcinoma Invest New Drugs. 2004 Nov;22 (4):475-80. doi: 10.1023/B:DRUG.0000036690.14585.a3. Authors Devansu Tewari 1 , Bradley J Monk , Mark Hunter , Camille A Falkner , Robert A Burger Affiliation dangers of x ray waves physicsWebCisplatin is a clinically advanced and highly effective anticancer drug used in the treatment of a wide variety of malignancies, such as head and neck, lung, testis, ovary, breast cancer, etc. birmingham v peterborough predictionWebOct 20, 2003 · Abstract. Cisplatin is one of the most potent antitumor agents known, … dangers of zero turn mowersWebOct 7, 2024 · Cisplatin is one of the most widely used chemotherapeutic drugs in the … dangers of working with electricityWebCisplatin is one of the most widely used antineoplastic agents in the treatment of solid tumour and haematological malignancies, including cancers of the testes, ovary, bladder, head and neck, oesophagus, stomach and lung, as well as lymphoma and osteosarcoma. dangers of yellowstone volcanoWebIntroduction: Cisplatin, a platinum-based antineoplastic agent, is the cornerstone for the … birmingham v peterboroughWebDec 1, 2024 · Methods. In this open-label, randomized, phase III study, newly diagnosed patients with advanced NSCLC were initially randomized (R1, 1:1) to receive first-line treatment with cisplatin 75 mg/m 2 plus docetaxel 75 mg/m 2 (DC75) or 60 mg/m 2 (DC60) for up to 4 cycles. Patients without progression were further randomized (R2, 1:2) to best … dangers of working on electric vehicles