WebNov 17, 2024 · Contexte: Le cisplatine, un agent utilisé en chimiothérapie pour traiter les tumeurs solides, entraîne de l’insuffisance rénale aiguë (IRA); un facteur de risque connu de néphropathie chronique et de mortalité. Le diagnostic de l’IRA repose sur des biomarqueurs qui ne sont mesurables qu’après l’apparition d’une lésion rénale et d’une déficience … WebCisplatin and fluorouracil (also called 5FU) is used to treat head and neck, oesophageal and anal cancer. It may sometimes be used to treat other cancers. It is best to read this information with our general information about chemotherapy and the type of cancer you have. Your doctor will talk to you about this treatment and its possible side ...
Cisplatin Cl2H6N2Pt - PubChem
WebDec 21, 2024 · Taken together, our investigation suggests that myo-inositol promotes CHIP-mediated ubiquitination of NOX4 to decelerate the process of ferroptosis, leading to the … Cisplatin has a number of side effects that can limit its use: • Nephrotoxicity (kidney damage) is the primary dose-limiting side effect and is of major clinical concern. Cisplatin selectively accumulates into the proximal tubule via basolateral-to-apical transport, where it disrupts mitochondrial energetics and endoplasmic reticulum Ca homeostasis and stimulates reactive oxygen species and pro-inflammatory cytokines. Multiple mitigation strate… smail fation
Overview of Chromatin Immunoprecipitation (ChIP) Cell …
WebSep 1, 2016 · La CHIP au cisplatine expose au risque d’IRA (13,3 %). Pour diminuer le risque de néphrotoxicité, il semble intéressant d’évaluer plus précisément la fonction … WebRevision date: 02-Jan-2007 Page 1 of 7 MATERIAL SAFETY DATA SHEET Version: 1.1 1. IDENTIFICATION OF THE SUBSTANCE/PREPARATION AND THE COMPANY/UNDERTAKING Material Name: Cisplatin Solution for Injection - … WebFor research use only. Cisplatin (NSC 119875, Cisplatinum, cis-diamminedichloroplatinum II, CDDP, cis DDP, DDP) is an inorganic platinum complex, which is able to inhibit DNA synthesis by conforming DNA … solicitar becas universitarias 2022 2023